Growth hormone and aging
نویسندگان
چکیده
منابع مشابه
Growth hormone, inflammation and aging
Mutant animals characterized by extended longevity provide valuable tools to study the mechanisms of aging. Growth hormone and insulin-like growth factor-1 (IGF-1) constitute one of the well-established pathways involved in the regulation of aging and lifespan. Ames and Snell dwarf mice characterized by GH deficiency as well as growth hormone receptor/growth hormone binding protein knockout (GH...
متن کاملGrowth hormone and aging: A challenging controversy
Although advanced age or symptoms of aging are not among approved indications for growth hormone (GH) therapy, recombinant human GH (rhGH) and various GH-related products are aggressively promoted as anti-aging therapies. Well-controlled studies of the effects of rhGH treatment in endocrinologically normal elderly subjects report some improvements in body composition and a number of undesirable...
متن کاملGrowth Hormone Replacement for Normal Aging
The purpose of this paper is to discuss whether or not growth hormone replacement therapy (GHRT) for the treatment of somatopause of normal aging is safe and effective. In order to determine this it is important to learn about GH, the benefits of GHRT, and its side-effects. We also need to discuss whether or not pathological GH deficiency is the same as GH deficiency caused by “normal aging.” T...
متن کاملPersian sturgeon growth hormone elaboration and purification
In this study Escherichia coli DE3 containing expression vector (pET21a) with cloned Persian sturgeon growth hormone (psGH) gene was grown in 10 mL LB broth on a 150 rpm shaker, at the temperature of 37 °C. At the late log phase (determined by OD standard curve) 100 &muL isopropyl &beta-D-1-thiogalactopyranoside (IPTG) was added for induction of GH synthesis. Samples were taken every 2 hours an...
متن کاملPersian sturgeon growth hormone elaboration and purification
In this study Escherichia coli DE3 containing expression vector (pET21a) with cloned Persian sturgeon growth hormone (psGH) gene was grown in 10 mL LB broth on a 150 rpm shaker, at the temperature of 37 °C. At the late log phase (determined by OD standard curve) 100 &muL isopropyl &beta-D-1-thiogalactopyranoside (IPTG) was added for induction of GH synthesis. Samples were taken every 2 hours an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: AGE
سال: 2000
ISSN: 0161-9152,1574-4647
DOI: 10.1007/s11357-000-0021-x